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- A female pirate and her companion race against their rivals to find a hidden island that contains a fabulous treasure.
- A woman flying to France to confront her straying fiance gets into trouble when the charming crook seated next to her uses her for smuggling.
- Lizzie McGuire, a clumsy middle school girl, navigates through teenage issues while enjoying her childhood years with genuine friends, an annoying younger brother and loving parents.
- A handsome New Orleans detective and a sexy district attorney heat things up in New Orleans--The Big Easy--as the two investigate crimes in a beleaguered police department.
- Carl is released from jail after serving a 5-year term and immediately sets about executing his next heist. The plan is relatively simple but time is critical. However, he doesn't factor in bad luck or the incompetence of his accomplices.
- After his wife's death, a world-traveling reporter decides to leave the busy rush of the big city and pack up his kids and move to a quiet little town in Wisconsin, where he takes a job as a columnist in the local paper. His kids don't adjust well to the move and his former boss keeps showing up to try to talk him into coming back. But he grows accustomed to his new home and new life.
- A little orphan girl catches the attention of a kind man named Mr. Warbucks, who wants to adopt her, but the cruel, strict orphanage owner has a scheme to keep Annie - and her reward money.
- Watters causes permanent damage when he participates in a charity boxing match. Diane intervenes when Billy wants to amputate a patient's leg. Dr. Grad suggests sewing maggots into the leg. Aaron and Camille make their divorce final.
- A potentially brain-dead donor comes into the ER. With doctors from all over Chicago waiting, the body is first declared brain-dead, then after a re-examination they find he's only in a coma. The doctors bicker over what to do.
- Nyland treats an amnesiac who wanders away and is mistaken by Phillip for an old medical student. Aaron operates on a death row inmate who begs Aaron to kill him on the table, dying before the state has a chance to execute him. McNeil suspects an old girlfriend of abusing her mother.
- Phillip travels to Wyoming to recruit Jack McNeil, an orthopedic surgeon. McNeil refuses, for reasons unknown. McNeil is haunted from memories of the Oklahoma City bombing. New Trauma chief Keith Wilkes is in hot water after he removes narcotics from a patient's intestine and flushes them. Grad returns from Africa and is offered a general practitioner position. Dr. Austin cares for her dying father. Ron Silver continues to appear.
- Nyland and Hancock deliver a Christmas present to Ricky Jackson for Kronk. Gunfire erupts while they're in the apartment, forcing the doctors to stay until the gunfire abates. While there, Nyland does his best to save a man impaled on a pipe, while Dennis braves bullets to bring in medical assistance. Diane worries that she might have contracted HIV from Bam-Bam, a laboratory animal. Camille is brought in after suffering a seizure while dancing. Billy treats a high-school baseball phenom with possible colon cancer.
- Watters is reunited with his Vietnam C.O. when the colonel is admitted suffering from rheumatoid arthritis. Phillip is baffled by the colonel's refusal to accept treatment. Kate has her hands full when Sara is traumatized by the accidental death of a Little League teammate. Wilkes and Nyland have a role reversal, with Danny staying calm and serene and Wilkes acting the hothead, over Ricky Jackson's use of ER supplies.
- Dr. Wilkes takes flak from Dennis for not giving back to his community. Billy has a tough decision to make when a childhood friend show up at his apartment in the early morning hours with a bullet in him. Diane believes Billy's friend may have been involved in a savage beating.
- Kronk and his dog move into Nyland's posh apartment after Billy's place burns down. Yvette White initially agrees to donate her late son's organs to others, but withdraws her consent when she discovers his heart will go to a Nazi-in-training. Birch finally gets up the nerve to invite Diane to lunch.
- Dr. Sutton is shocked when his three ex-wives arrive at the same time, two of him tell him they're lovers, the other is admitted to the ER. Austin pursues the chief of surgery office with zeal. Hancock's sister comes in after being beaten by her husband. Danny Nyland hits on the fiancée of a wealthy patient.
- Laurie invites Jeffrey, Aaron, and Camille to her wedding, which needs to be held soon due to the minister's impending transfer out of the asylum. Dr. Sutton operates on a fetus. Birch and Watters testify at a hearing on medicare, but are surprised when they're ambushed by a politically minded senator. Camille displays signs of depression.
- Phillip and Aaron present their plan to buy Chicago Hope to the staff, where it's met with resounding complaints. Aaron tries to define his relationship with Maricela. The ER treats a patient with numerous psychosomatic ailments. Kronk gets in trouble when he performs a lung reduction operation, a procedure vetoed by the patient's HMO. Billy visits the patient's HMO representative, the 'freaky' Jonathan Saunders, to straighten things out.
- Aaron and psychiatrist Bix Konstadt plan to operate on a young boy with obsessive compulsive disorder in an attempt to cure him. Aaron worries when Bix admits she's a manic depressive off her medication. Watters, Nyland and Kronk have their hands full with a woman who may have been abducted by aliens. Heart transplant recipient Henry Alden (#34) is brought in complaining of pain. Alden insists on speaking to Robert Malzone, the husband of the woman who donated the heart.
- Jeffrey is distinctly unpopular with his fellow surgeons in the wake of his psychological problems. Jeffrey operates on one of Hancock's patients. Nyland performs the wrong operation on a patient. Birch offends everyone in his parenting class by offering unsolicited advice. Shutt's father brings a patient to Chicago Hope in the hopes Aaron will operate on her. Dr. Kronk participates in a charity bachelor auction, where he's 'purchased' by Dr. Kate Austin, new CT surgeon at the hospital.
- Billy returns from Africa, leaving the peaceful Maasai for America's turbulence. Billy is threatened by a 12-year-old after his drug-dealing brother, under Billy's care, dies. Austin faces the impact of her actions when she and her co-workers are sued in the Harrod death (ep #32). Aaron finds himself ill at ease about an upcoming date with physical therapist Karen Wilder.
- Jeffrey Geiger returns, bearing the news that he's a partner in the newly formed Hope Health Care. Kate bears with Jeffrey's advice in a critical heart transplant operation. Wilkes takes a wild helicopter ride to fetch the donor heart. Dr. Kronk tries to find a solution for his Alzheimer's afflicted father. McNeil and Shutt pontificate about life and religion following a patient's claim that she was healed by a vision of the virgin mother.
- Assistant State's Attorney Charles Lamb interviews Chicago Hope staffers Wilkes, Nyland, McNeil, and Watters to determine responsibility in the death of a patient.
- Kate is incensed when her ex-husband, Tommy Wilmette, announces plans to buy the hospital. Danny treads thin ice when he continues his relationship with Valerie. Kate tries to convince wealthy patient Jack Calverton to buy Chicago Hope before Wilmette does. Hancock's brother-in-law visits his battered wife, taunting Dennis.
- Geiger desperately attempts to save Birch's life after he is senselessly gunned down by street thugs.
- The hospital endures Kate's massive ego when she's followed by a newspaper reporter. Jack tries to save a dying child against the parent's explicit wishes and later falls deeply into debt. Both Billy and Diane have second thoughts about their engagement.
- Life is tough for the senior doctors, with Shutt being treated like a second class citizen in the hospital and Austin learning she's been reinstated but with a substantial pay cut, a different title, and a much smaller office. Aaron tries to develop his shunt, with input from new resident Dr. Carr. Jack treats an elderly man who tries to set McNeil's priorities straight. The hospital hires a publicist to create a promotional video, which in the end, seems vaguely familiar.
- Bix is reduced to a mere shell of herself without her lithium. Aaron goes ahead with the procedure on Eric Dipretto. Kronk files a sexual harassment suit against Austin after she bullies him yet again. Nyland and Billy try to perform an intestinal transplant against Austin's and Watter's wishes. Dr. Austin campaigns for head of surgery.
- Dr. Watters treats a mother with a mystifying liver ailment. Nyland and Austin return to the hospital for suspension hearings. Dr. Shutt begins to fear he's attracted to his male research assistant. Dennis and McNeil treat an aspiring Olympic cyclist with pain in her knees.
- Jack has his hands full with two of Karen's patients, Harriet Owens, who hasn't moved out of his house yet, and the delusional Luke Sarison, who believes McNeil is his father. Aaron and Kate vie for chief of surgery. Phillip is invited to join his latest girlfriend, Emma, when she moves to Paris. Danny Nyland is arrested for the Jessup death, and subsequently transferred from the ER to the blood bank.
- Kate's friend, feminist professor Marina, tries desperately to 'get pregnant' but has to work against, rather than with, her husband. Aaron works against Tommy Wilmette in an attempt to get his friend, David, approved for a controversial gene therapy treatment. Diane tries to get marijuana for an ill patient.
- Kate and Tommy travel to Washington D.C. to speak out on Health Care Reform. Marina arranges to adopt the child of a pregnant teenager. Jack treats the incredibly annoying woman.
- Jack, re-energized by his descent into gambling, performs a daring procedure, attaching a man's left hand onto his right arm. Aaron treats a man who, after surgery, completely forgets the last ten years of his life and speaks in loving terms about his now ex-wife. Aaron loses his cool when his car is stalked by an irate man who feels Aaron personally wronged him by inadvertently parking too close to his van. Diane examines a mummy.
- Nyland returns from his vacation with Valerie to find he's been suspended and replaced as chief of trauma by Dr. Keith Wilkes. Kate comes back from New Zealand facing both kidnapping charges and a suspension. A new group of interns comes into the hospital, eager to change things. Uncertainty hangs in the air over the future of the hospital when Tommy Wilmette considers drastic cuts. Billy and Diane work in a Maasai village in Africa. Aaron and Phillip clash when Aaron becomes 'buddy buddy' with Wilmette.
- Aaron and Dr. McNeil clash when the two have conflicting ideas for a patient's treatment. Diane struggles with the transition from animal research to treating patients when she has a needy patient. Kate is car-jacked, loses her father's ashes, and gets on Tommy's bad side again.
- Nyland, fresh off his injury leave, puts all his energy into identifying an assault victim. Billy has qualms when a patient who tested positive for the breast cancer gene asks him to perform a preventive double mastectomy. Kate tries to get Sara into an exclusive school. Diane proposes to Billy.
- Dr. Geiger and his clown troupe entertain injured children. Ricky Jackson, Billy's ghetto protege, visits the ER for a look at real medicine. A psychotic, abusive, insane family of four pays a visit to the ER when a session with their therapist really goes bad.
- Dennis is vilified by the media when he performs an abortion to save a mother's life. The mother sues, despite the fact that she gave consent, plus the fact that the child was already dead. Dr. Kronk treats a female impersonator suffering from AIDS. Nyland has his hands full with an abandoned six-year-old.
- The wife of a comatose patient seeks to impregnate herself to preserve her husband's legacy. Nyland squares off against a patient when he refuses to fill her Demerol prescription. An inquisitive Kronk discovers that Nyland is the one who got the patient hooked on the drug in the first place. It's a battle of egos when Geiger meets with Austin. Aaron and Camille mutually agree on divorce. Alicia, Alan's child, has her baptism.
- The whole staff comes together when Danny Nyland is horribly injured in a car accident. Austin tries to get a heart transplant for a Pulitzer Prize winning author who's already received, and abused, a heart transplant. Jack falls deeper into gambling.
- Camille comforts a rape victim while Austin, who is a colleague of the accused rapist, refuses to believe the alleged victim. Billy and Diane counsel a newlywed couple on the best ways to engage themselves in bed. Sutton is in disbelief when he discovers Dennis has been tolerating a 30-year-old dating and living with a 14-year-old. Finally, Shutt is the victim of mistaken identity when a 3rd year resident mistakenly assumes Shutt is gay.
- Dr. Wilkes copes with personal and professional problems as he tries to reach a compromise with his wife regarding an unexpected pregnancy while trying to convince a suicidal patient he pulled out of the river that a crippling operation is his only chance for life. Aaron takes revenge against a deadbeat debtor by taking his money's worth from the patient's clothing store. Dr. Austin falls for a visiting dignitary.
- Dr. Watters remains 'sick' three days after Birch's death. Alan's sister Marguerite surprises Phillip, striking up an immediate friendship with him. Dr. Austin, the interim 'interim chief of staff', abuses her power to first stop a procedure, then give it the go-ahead. The unconventional procedure, performed on Multiple Sclerosis patient Joe Springer, goes forward. Diane, still suffering from the effects of the shooting, is sent home by Kate. Austin later reveals that she was raped many years ago, trying to let Diane know that she knows what it feels like to be powerless. The new obstetrician throws a 'healing' party to try to help the staff attain closure with Jeffrey.
- Kronk and Grad wake up in bed together. Diane finds out about Kronk's night with Kate. Dr. Watters treats a young girl suffering from kidney damage. Watters tries to bring her feuding parents together to help her psyche. Kate discovers her ex-husband plans to move to Boston with Sara. Camille invites Dennis on a date.
- Aaron reunites with an old friend, David, who has only a few months left to live. His friend suggests Aaron marry his wife, who married David over Aaron, after David dies. Aaron gets drunk and runs into (imagines?) Jeffrey. Wilkes doubts his wife when she claims to have had a miscarriage. Wilkes and Nyland's feud escalates after a patient dies. Jack refuses to listen to Phillip when he offers to help Jack overcome his gambling problem, but later asks Karen Wilder to help him. Aaron tries to figure out what to do about Maricela.
- Billy and Diane are caught in the middle of a hostage situation after two revolutionaries shoot up a political convention. Dr. Kronk risks his life to treat a wounded rebel, while the other criminals grow increasingly tense.
- Dr. Austin is to blame when she inadvertently leaves a clamp inside a patient that later dies. Kate struggles over the dilemma of whether to stay silent and protect both herself and the hospital, or tell the patient's parents. Billy and Danny search for a street 'doctor', after one of his patients is brought in with severe internal damage. Dr. Grad successfully inoculates an ape with the AIDS virus using a vaccine she created. Harold Aldrich is temporarily hired as Birch's replacement. Camille asks Nyland to write her a prescription for sleeping pills.
- Dr. Austin struggles to make her father, a Christian Scientist, listen to reason when he refuses to let her operate on his heart. Aaron grapples with his feelings toward his father in the wake of his death. Meanwhile, Dr. Sutton delivers a child of indeterminate gender, forcing the infant's parents to make a difficult decision. Jeffrey Geiger provides comic relief, returning as a member of a performing clown troupe.
- Aaron meets man who claims to be his real father. After learning the truth from his mother and talking to Phillip he tries to get to know the man. And at the same Phillip tries to establish contact with his son.