Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "down-syndrome"
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1. American Horror Story (2011– )
TV-MA | 60 min | Drama, Horror, Sci-Fi
An anthology series centering on different characters and locations, showcasing different aspects of horror.
Stars: Lady Gaga, Kathy Bates, Angela Bassett, Sarah Paulson
Votes: 343,599
2. Mare of Easttown (2021)
TV-MA | 60 min | Crime, Drama, Mystery
A detective in a small Pennsylvania town investigates a local murder while trying to keep her life from falling apart.
Stars: Kate Winslet, Julianne Nicholson, Jean Smart, Angourie Rice
Votes: 187,681
3. The Virgin Suicides (1999)
R | 97 min | Drama, Romance
A group of male friends become obsessed with five mysterious sisters who are sheltered by their strict, religious parents in suburban Detroit in the mid 1970s.
Director: Sofia Coppola | Stars: Kirsten Dunst, Josh Hartnett, James Woods, Kathleen Turner
Votes: 169,189 | Gross: $4.86M
4. Rain Man (1988)
R | 133 min | Drama
After a selfish L.A. yuppie learns his estranged father left a fortune to an autistic-savant brother in Ohio that he didn't know existed, he absconds with his brother and sets out across the country, hoping to gain a larger inheritance.
Director: Barry Levinson | Stars: Dustin Hoffman, Tom Cruise, Valeria Golino, Gerald R. Molen
Votes: 546,576 | Gross: $178.80M
5. The Peanut Butter Falcon (2019)
PG-13 | 97 min | Adventure, Comedy, Drama
Zak, a man with down syndrome, runs away from a residential nursing home to pursue his dream of becoming a wrestler. Later, he meets with an outlaw who becomes his friend and coach.
Directors: Tyler Nilson, Michael Schwartz | Stars: Zack Gottsagen, Ann Pierce, Dakota Johnson, Bruce Dern
Votes: 103,198 | Gross: $13.12M
6. Waiting... (I) (2005)
R | 94 min | Comedy
Young employees at ShenaniganZ restaurant collectively stave off boredom and adulthood with their antics.
Director: Rob McKittrick | Stars: Ryan Reynolds, Anna Faris, John Francis Daley, Justin Long
Votes: 106,140 | Gross: $16.12M
7. EastEnders (1985– )
TV-PG | 30 min | Crime, Drama, Romance
The everyday lives of working-class inhabitants of Albert Square, a traditional Victorian square of terrace houses surrounding a park in the East End of London's Walford borough. The square includes the Queen Vic pub and a street market.
Stars: Adam Woodyatt, Steve McFadden, Letitia Dean, June Brown
Votes: 9,222
8. Precious (II) (2009)
R | 110 min | Drama
In New York City's Harlem circa 1987, an overweight, abused, illiterate teen who is pregnant with her second child is invited to enroll in an alternative school in hopes that she can re-route her life in a better direction.
Director: Lee Daniels | Stars: Gabourey Sidibe, Mo'Nique, Paula Patton, Mariah Carey
Votes: 116,240 | Gross: $47.57M
9. Champions (2023)
PG-13 | 124 min | Comedy, Drama, Sport
A former minor-league basketball coach is ordered by the court to manage a team of players with intellectual disabilities. He soon realizes that despite his doubts, together, this team can go further than they ever imagined.
Director: Bobby Farrelly | Stars: Woody Harrelson, Kaitlin Olson, Matt Cook, Ernie Hudson
Votes: 25,984
10. Wild (I) (2014)
R | 115 min | Adventure, Biography, Drama
A chronicle of one woman's 1,100-mile solo hike undertaken as a way to recover from a recent personal tragedy.
Director: Jean-Marc Vallée | Stars: Reese Witherspoon, Laura Dern, Gaby Hoffmann, Michiel Huisman
Votes: 138,849 | Gross: $37.88M
11. Life Goes On (1989–1993)
TV-PG | 60 min | Drama
A modern All-American family deals with the struggles of life and love in mid-western suburbia.
Stars: Kellie Martin, Chris Burke, Patti LuPone, Bill Smitrovich
Votes: 2,919
12. I Am Sam (2001)
PG-13 | 132 min | Drama
An intellectually disabled man fights for custody of his 7-year-old daughter and in the process teaches his cold-hearted lawyer the value of love and family.
Director: Jessie Nelson | Stars: Sean Penn, Michelle Pfeiffer, Dakota Fanning, Dianne Wiest
Votes: 155,304 | Gross: $40.31M
13. Notes on a Scandal (2006)
R | 92 min | Crime, Drama, Romance
A veteran high school teacher befriends a younger art teacher, who is having an affair with one of her fifteen-year-old students. However, her intentions with this new "friend" also go well beyond a platonic friendship.
Director: Richard Eyre | Stars: Cate Blanchett, Judi Dench, Andrew Simpson, Tom Georgeson
Votes: 84,571 | Gross: $17.51M
14. The Kingdom (1994–2022)
TV-MA | 60 min | Comedy, Drama, Fantasy
Doctors at an ultramodern hospital in Denmark become convinced, by way of weird, inexplicable happenings, that the place is haunted.
Stars: Ernst-Hugo Järegård, Kirsten Rolffes, Ghita Nørby, Søren Pilmark
Votes: 20,346 | Gross: $0.09M
15. I'm Not Ashamed (2016)
PG-13 | 112 min | Biography, Drama
The true story of Rachel Joy Scott, the first student killed in the Columbine High School shooting on April 20, 1999.
Director: Brian Baugh | Stars: Masey McLain, Ben Davies, Cameron McKendry, Terri Minton
Votes: 4,177 | Gross: $2.08M
16. Where Hope Grows (2014)
PG-13 | 95 min | Drama, Family
A baseball player whose professional career was cut short due to his personal problems is suddenly awakened and invigorated by a young-man with Down syndrome who works at the local grocery store.
Director: Chris Dowling | Stars: Kristoffer Polaha, David DeSanctis, McKaley Miller, Michael Grant
Votes: 3,861 | Gross: $1.10M
17. Breakfast on Pluto (2005)
R | 128 min | Comedy, Drama
In the 1970s, a young trans woman, Patrick "Kitten" Braden, comes of age by leaving her Irish town for London, in part to look for her mother and in part because her gender identity is beyond the town's understanding.
Director: Neil Jordan | Stars: Cillian Murphy, Morgan Jones, Eva Birthistle, Liam Neeson
Votes: 24,531 | Gross: $0.83M
18. The Ringer (2005)
PG-13 | 94 min | Comedy, Sport
A young guy's only option to erase a really bad debt is to rig the Special Olympics by posing as a contestant.
Director: Barry W. Blaustein | Stars: Johnny Knoxville, Katherine Heigl, Brian Cox, Jed Rees
Votes: 38,826 | Gross: $35.42M
19. The White Ribbon (2009)
R | 144 min | Drama, Mystery, Thriller
Strange events happen in a small village in the north of Germany during the years before World War I, which seem to be ritual punishment. Who is responsible?
Director: Michael Haneke | Stars: Christian Friedel, Ernst Jacobi, Leonie Benesch, Ulrich Tukur
Votes: 77,649 | Gross: $2.22M
20. Welcome to the Dollhouse (1995)
R | 88 min | Comedy, Drama
An awkward seventh-grader struggles to cope with inattentive parents, snobbish class-mates, a smart older brother, an attractive younger sister and her own insecurities in suburban New Jersey.
Director: Todd Solondz | Stars: Heather Matarazzo, Christina Brucato, Victoria Davis, Christina Vidal
Votes: 37,170 | Gross: $4.77M
21. Sharp Stick (2022)
R | 92 min | Comedy
Sarah Jo is a naive 26-year-old living on the fringes of Hollywood with her mother and sister. She just longs to be seen. When she begins an affair with her older employer, she is thrust into an education on sexuality, loss and power.
Director: Lena Dunham | Stars: Kristine Froseth, Jon Bernthal, Luka Sabbat, Scott Speedman
Votes: 2,095
22. LOL (2012)
PG-13 | 97 min | Comedy, Drama, Romance
As a new year at school begins, Lola's heart is broken by her boyfriend, though soon she's surprised by her best friend, promising musician Kyle, who reveals his feelings for her.
Director: Lisa Azuelos | Stars: Miley Cyrus, Douglas Booth, Ashley Greene, Demi Moore
Votes: 58,139 | Gross: $0.05M
23. Stumptown (2019–2020)
TV-14 | 44 min | Crime, Drama, Mystery
A sharp-witted Marine veteran becomes a private investigator in Portland, Oregon, where she takes care of her brother who has Down syndrome.
Stars: Cobie Smulders, Jake Johnson, Tantoo Cardinal, Cole Sibus
Votes: 13,073
24. Santa Sangre (1989)
NC-17 | 123 min | Drama, Horror, Thriller
A former circus artist escapes from a mental hospital to rejoin his armless mother - the leader of a strange religious cult - and is forced to enact brutal murders in her name as he becomes "her arms".
Director: Alejandro Jodorowsky | Stars: Axel Jodorowsky, Blanca Guerra, Guy Stockwell, Thelma Tixou
Votes: 23,328
25. The Casagrandes (2019–2022)
TV-Y7 | 22 min | Animation, Short, Adventure
Spin-off of "The Loud House (2014)" featuring Ronnie Anne Santiago, who moves to the big city with her mother and older brother Bobby and meets her extended Hispanic family.
Stars: Carlos Alazraqui, Izabella Alvarez, Alex Cazares, Ruben Garfias
Votes: 1,695
26. Just Before I Go (2014)
R | 95 min | Comedy, Drama
On the verge of giving up on life, a guy travels to his hometown to make amends.
Director: Courteney Cox | Stars: Seann William Scott, Olivia Thirlby, Garret Dillahunt, Kate Walsh
Votes: 19,480 | Gross: $0.01M
27. The Memory Keeper's Daughter (2008 TV Movie)
TV-14 | 90 min | Drama
A father separates his son from his twin sister at birth to prevent him and the mother from knowing she was born with Down syndrome. Based on the novel by Kim Edwards.
Director: Mick Jackson | Stars: Emily Watson, Dermot Mulroney, Hugh Thompson, Krystal Hope Nausbaum
Votes: 3,032
28. Adam's Apples (2005)
R | 94 min | Comedy, Crime, Drama
A neo-Nazi sentenced to community service at a church clashes with the blindly devoted minister.
Director: Anders Thomas Jensen | Stars: Ulrich Thomsen, Mads Mikkelsen, Nicolas Bro, Paprika Steen
Votes: 54,623 | Gross: $0.00M
29. The Seventh Sign (1988)
R | 97 min | Drama, Fantasy, Horror
Abby Quinn is eagerly awaiting childbirth but is haunted by dreams where she suffers a miscarriage. When she decides to rent a room to a mysterious stranger, she realizes a chain of events that will unleash the end of humanity.
Director: Carl Schultz | Stars: Demi Moore, Michael Biehn, Jürgen Prochnow, Peter Friedman
Votes: 15,677 | Gross: $18.88M
30. Miss Marple: The Mirror Crack'd from Side to Side (1992 TV Movie)
TV-14 | 106 min | Crime, Drama, Mystery
At a reception for a fading film star making a screen comeback, a gushing, pushy fan is poisoned by a drink apparently meant for the actress.
Director: Norman Stone | Stars: Joan Hickson, Claire Bloom, Barry Newman, Norman Rodway
Votes: 2,030
31. Game Change (2012 TV Movie)
TV-MA | 118 min | Biography, Drama, History
Governor Sarah Palin of Alaska becomes Senator John McCain's running mate in the 2008 Presidential election.
Director: Jay Roach | Stars: Ed Harris, Julianne Moore, Woody Harrelson, Peter MacNicol
Votes: 23,205
32. Kingdom Hospital (2004)
608 min | Drama, Fantasy, Horror
The quirky staff and patients of an ultramodern (albeit increasingly dilapidated) Maine hospital gradually become familiar with the supernatural occurrences that take place there, uncovering a dark secret in the process.
Stars: Jamie Harrold, Diane Ladd, Bruce Davison, Jack Coleman
Votes: 7,942
33. Running with Scissors (2006)
R | 116 min | Comedy, Drama
A teenage boy comes of age in the 1970's, sent by his neurotic, pretentious mother to live with a jolly, vulgar psychiatrist and his eccentric extended family.
Director: Ryan Murphy | Stars: Joseph Cross, Annette Bening, Brian Cox, Gwyneth Paltrow
Votes: 23,164 | Gross: $6.75M
34. Summer Heights High (2007)
TV-MA | 28 min | Comedy, Drama, Family
The life of a public school epitomized by disobedient student Jonah Takalua, self-absorbed private school exchange student Ja'mie King, and megalomaniac drama teacher Mr. G.
Stars: Chris Lilley, Asolima Tauati, Iro Utaifeau, Zach Fa'atoe
Votes: 15,098
35. Wakefield (2016)
R | 106 min | Drama
A lawyer on the edge of madness decides to disassociate himself from his own life.
Director: Robin Swicord | Stars: Bryan Cranston, Jennifer Garner, Victoria Bruno, Ellery Sprayberry
Votes: 18,051 | Gross: $0.26M
36. All the Real Girls (2003)
R | 108 min | Drama, Romance
Small-town love story of a young man with a reputation for womanizing and his best friend's sister.
Director: David Gordon Green | Stars: Zooey Deschanel, Paul Schneider, Patricia Clarkson, Shea Whigham
Votes: 11,032 | Gross: $0.55M
37. Jan Dara (2001)
108 min | Drama, Romance
Jan Dara grows up in a house devoid of love, but rich in lust. He soon takes up the sinful lifestyle of his stepfather, Khun Luang, who married his mother after she was raped.
Director: Nonzee Nimibutr | Stars: Santisuk Promsiri, Christy Chung, Wipawee Charoenpura, Eakarat Sarsukh
Votes: 2,446
38. Fair City (1989– )
25 min | Drama
The day-to-day dramas of the community who live and work in the fictional north Dublin suburb of Carrigstown.
Stars: Mick Nolan, Philip Michael, Rodrigo Ternevoy, Alexander Lester
Votes: 673
39. The Aristocrats (2005)
Not Rated | 89 min | Documentary, Comedy
One hundred superstar comedians tell the same very, VERY dirty, filthy joke--one shared privately by comics since Vaudeville.
Directors: Penn Jillette, Paul Provenza | Stars: George Carlin, Don Rickles, Chris Rock, Chris Albrecht
Votes: 17,060 | Gross: $6.38M
40. Café de Flore (2011)
Not Rated | 120 min | Drama, Romance
A love story between a man and woman. And between a mother and her son. A mystical and fantastical odyssey on love.
Director: Jean-Marc Vallée | Stars: Vanessa Paradis, Kevin Parent, Hélène Florent, Evelyne Brochu
Votes: 16,716
41. Palindromes (2004)
Not Rated | 100 min | Comedy, Drama
Aviva is thirteen, awkward and sensitive. Her mother Joyce is warm and loving, as is her father, Steve, a regular guy who does have a fierce temper from time to time. The film revolves around her family, friends and neighbors.
Director: Todd Solondz | Stars: Jennifer Jason Leigh, Ellen Barkin, Stephen Adly Guirgis, Matthew Faber
Votes: 12,868 | Gross: $0.55M
42. Please Give (2010)
R | 87 min | Comedy, Drama
In New York City, a husband and wife butt heads with the granddaughters of the elderly woman who lives in the apartment the couple owns.
Director: Nicole Holofcener | Stars: Catherine Keener, Oliver Platt, Rebecca Hall, Elizabeth Keener
Votes: 11,586 | Gross: $4.03M
43. Coffee Town (2013)
Not Rated | 87 min | Comedy
A website manager enlists the help of his two friends in order to convince the owners of his favorite coffee shop -- which doubles as his office -- not to turn their business into a bar.
Director: Brad Copeland | Stars: Glenn Howerton, Steve Little, Ben Schwartz, Josh Groban
Votes: 5,278
44. Neon Heart (2018)
86 min | Drama
Laura and Niklas are handicap helpers. She was in porn and he in detox. Laura tries to speak with her ex, Niklas. Niklas tries to speak with his teen brother, who's in bad company.
Director: Laurits Flensted-Jensen | Stars: Vic Carmen Sonne, Karen Sigrid Arild Albrechtsen, Nicklas Svale Andersen, Christian Andersen Busk
Votes: 340
45. Any Day Now (I) (2012)
R | 98 min | Drama
In the 1970s, a gay couple fights a biased legal system to keep custody of the abandoned mentally handicapped teenager that comes to live under their roof.
Director: Travis Fine | Stars: Alan Cumming, Garret Dillahunt, Isaac Leyva, Frances Fisher
Votes: 6,575 | Gross: $0.20M
46. The Eighth Day (1996)
118 min | Comedy, Drama
An unusual and wonderful friendship develops between a busy but unhappy salesman and a resident of a mental asylum.
Director: Jaco Van Dormael | Stars: Daniel Auteuil, Pascal Duquenne, Miou-Miou, Henri Garcin
Votes: 10,080 | Gross: $0.33M
47. The Crown Jewels (2011)
120 min | Drama
When she's arrested for attempting to murder the son of a factory owner, Fragancia spins a tale of love and betrayal that began in her youth.
Director: Ella Lemhagen | Stars: Alicia Vikander, Bill Skarsgård, Loa Falkman, Noah Byström
Votes: 2,938
48. Spare Room (2018)
97 min | Drama
When a young widow rents a room to a mysterious veteran, their attraction sparks unforeseen circumstances.
Director: Jenica Bergere | Stars: Skyler Samuels, Martin Sensmeier, Thomas Cocquerel, Cole Sibus
Votes: 357
49. Shooting Fish (1997)
PG | 103 min | Comedy, Crime, Romance
Two con artists' plan to steal enough for a house are twisted when a pretty girl enters the picture.
Director: Stefan Schwartz | Stars: Dan Futterman, Stuart Townsend, Kate Beckinsale, Rowena Cooper
Votes: 7,850 | Gross: $0.30M
50. Jonathan: The Boy Nobody Wanted (1992 TV Movie)
100 min | Biography, Drama
A down-syndrome boy is left in an institute by his parents. Ginny, who works in the institute wants to have custody over Jonathan but has to fight the system and the parents.
Director: George Kaczender | Stars: JoBeth Williams, Chris Burke, Jeffrey DeMunn, Tom Mason
Votes: 105