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- CreatorDarren StarStarsSarah Jessica ParkerKim CattrallKristin DavisFour female New Yorkers gossip about their sex lives (or lack thereof) and find new ways to deal with being a woman in the late 1990s.
- CreatorJ.J. AbramsStarsJennifer GarnerRon RifkinCarl LumblySydney Bristow is an international spy recruited out of college, trained for espionage and self-defense.
- CreatorMark SchwahnStarsChad Michael MurrayJames LaffertyHilarie Burton MorganHalf-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina.
- CreatorJosh SchwartzStarsMischa BartonAdam BrodyPeter GallagherA troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- CreatorKevin WilliamsonStarsJames Van Der BeekKatie HolmesMichelle WilliamsTwo childhood best friends, Dawson and Joey, go through different stages of adolescence together. Their friendship is later tested when they both start a relationship with different people.
- CreatorDavid ShoreStarsHugh LaurieOmar EppsRobert Sean LeonardUsing a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- CreatorTim KringStarsJack ColemanHayden PanettiereMilo VentimigliaCommon people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- CreatorMarc CherryStarsTeri HatcherFelicity HuffmanMarcia CrossSecrets and truths unfold through the lives of female friends in one suburban neighborhood after the mysterious suicide of a neighbor.
- CreatorPaul T. ScheuringStarsDominic PurcellWentworth MillerAmaury NolascoA structural engineer installs himself in a prison he helped design, in order to save his falsely accused brother from a death sentence by breaking themselves out from the inside.
- CreatorJ.J. AbramsJeffrey LieberDamon LindelofStarsJorge GarciaJosh HollowayYunjin KimThe survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island.
- CreatorStephanie SavageJosh SchwartzStarsBlake LivelyLeighton MeesterPenn BadgleyPrivileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- CreatorAlfred GoughMiles MillarStarsTom WellingMichael RosenbaumAllison MackA young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- CreatorChuck LorreBill PradyStarsJohnny GaleckiJim ParsonsKaley CuocoA woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
- StarsVinicio MarchioniAlessandro RojaMarco BocciThis crime drama, set in Rome in the 1970s, tells the story of the Banda della Magia, a prolific Italian crime family responsible for some of the country's most violent crimes.
- CreatorAndrew LenchewskiJohn P. RogersStarsMark FeuersteinPaulo CostanzoReshma ShettyAn unfairly discredited but brilliant ER doctor winds up working with his younger brother in the Hamptons as a concierge doctor to the uber-rich and ultra-elite.
- CreatorJ.J. AbramsAlex KurtzmanRoberto OrciStarsAnna TorvJoshua JacksonJohn NobleAn F.B.I. agent is forced to work with an institutionalized scientist and his son in order to rationalize a brewing storm of unexplained phenomena.
- CreatorJulie PlecKevin WilliamsonStarsNina DobrevPaul WesleyIan SomerhalderThe lives, loves, dangers and disasters in the town, Mystic Falls, Virginia. Creatures of unspeakable horror lurk beneath this town as a teenage girl is suddenly torn between two vampire brothers.
- CreatorIan BrennanBrad FalchukRyan MurphyStarsLea MicheleJane LynchMatthew MorrisonA group of ambitious misfits try to escape the harsh realities of high school by joining a glee club headed by a passionate Spanish teacher.
- CreatorSamuel BaumStarsTim RothKelli WilliamsBrendan HinesAbout Cal Lightman, the world's leading deception expert who studies facial expressions and involuntary body language to expose the truth behind the lies.
- StarsIan McShaneMatthew MacfadyenEddie RedmayneSet against a backdrop of war, religious strife and power struggles which tears lives and families apart.
- StarsChris VanceFrançois BerléandCharly HübnerFrank Martin is an ex special ops, who now spends his life as a transporter on the other side of the law. With three rules, he always completes his contracts. One way, or the other.
- CreatorBrenda HamptonStarsShailene WoodleyMolly RingwaldIndia Eisley15 year old Amy ends up pregnant after one night at band camp, throwing her whole life upside down. It doesn't help that she's now going to school with that guy.
- CreatorEric KripkeStarsJared PadaleckiJensen AcklesJim BeaverTwo brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- CreatorBrannon BragaDavid S. GoyerStarsCourtney B. VanceJoseph FiennesJack DavenportA special task force in the FBI investigates after every person on Earth simultaneously blacks out and awakens with a short vision of their future.
- CreatorMichael CurtisRoger S.H. SchulmanStarsKevin JonasChelsea KaneNicole Gale AndersonThe show follows the Jonas Brothers through fun and unusual situations as they try to live ordinary lives.