A depressed musician reunites with his lover. However, their romance, which has already endured several centuries, is disrupted by the arrival of her uncontrollable younger sister.
As the extremely withdrawn Don Johnston is dumped by his latest woman, he receives an anonymous letter from a former lover informing him that he has a son who may be looking for him. A freelance sleuth neighbor moves Don to embark on a cross-country search for his old flames in search of answers.
On the run after murdering a man, accountant William Blake encounters a strange Native American man named Nobody who prepares him for his journey into the spiritual world.