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- DirectorMarek KanievskaStarsAndrew McCarthyJami GertzRobert Downey Jr.A college freshman returns to L.A. for the holidays at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.
- DirectorGus Van SantStarsMatt DillonKelly LynchJames Le GrosA pharmacy-robbing dope fiend and his crew pop pills and evade the law.
- DirectorHarold BeckerStarsJames WoodsSean YoungJohn KapelosA real estate developer who enjoyed short-lived success seeks to regain his edge by using cocaine, but takes himself to new lows as he gets lost in the downward spiral of drug addiction.
- DirectorGus Van SantStarsMichael PittLukas HaasAsia ArgentoA Seattle musician's life and career are reminiscent of those of Kurt Cobain.
- DirectorTed DemmeStarsJohnny DeppPenélope CruzFranka PotenteThe story of how George Jung, along with the Medellín Cartel headed by Pablo Escobar, established the American cocaine market in the 1970s in the United States.
- DirectorScott KalvertStarsLeonardo DiCaprioLorraine BraccoMarilyn SokolA teenager finds his dreams of becoming a basketball star threatened after he free falls into the harrowing world of drug addiction.
- DirectorJay ChandrasekharStarsJay ChandrasekharKevin HeffernanAndré VippolisFive Vermont state troopers, avid pranksters with a knack for screwing up, try to save their jobs and out-do the local police department by solving a crime.
- DirectorOliver StoneStarsVal KilmerMeg RyanKyle MacLachlanThe story of the famous and influential 1960s rock band The Doors and its lead singer and composer, Jim Morrison, from his days as a UCLA film student in Los Angeles, to his untimely death in Paris, France at age 27 in 1971.
- DirectorFernando MeirellesKátia LundStarsAlexandre RodriguesLeandro FirminoMatheus NachtergaeleIn the slums of Rio, two kids' paths diverge as one struggles to become a photographer and the other a kingpin.
- DirectorAlex CoxStarsGary OldmanChloe WebbDavid HaymanThe relationship between Sid Vicious, bassist for British punk group Sex Pistols, and his girlfriend Nancy Spungen is portrayed.
- DirectorPaul Thomas AndersonStarsMark WahlbergJulianne MooreBurt ReynoldsBack when sex was safe, pleasure was a business and business was booming, an idealistic porn producer aspires to elevate his craft to an art when he discovers a hot young talent.
- DirectorLarry ClarkStarsLeo FitzpatrickJustin PierceChloë SevignyA day in the life of a group of teens as they travel around New York City skating, drinking, smoking and deflowering virgins.
- DirectorMichael WadleighStarsJoan BaezRichie HavensRoger DaltreyOscar-winning musical chronicle that brilliantly captures the three-day rock concert and celebration of peace and love that became a capstone for the Sixties.
- DirectorAlbert HughesAllen HughesStarsTyrin TurnerLarenz TateJune Kyoto LuA young street hustler attempts to escape the rigors and temptations of the ghetto in a quest for a better life.
- DirectorJoe CarnahanStarsRay LiottaJason PatricChi McBrideWhen the trail goes cold on a murder investigation of a policeman, an undercover narcotics officer is lured back to the force to help solve the case.
- DirectorAlejandro G. IñárrituStarsSean PennBenicio Del ToroNaomi WattsA freak accident brings together a critically ill mathematician, a grieving mother, and a born-again ex-con.
- DirectorFelix van GroeningenStarsSteve CarellMaura TierneyJack Dylan GrazerBased on the best-selling pair of memoirs from father and son David and Nic Sheff, Beautiful Boy chronicles the heartbreaking and inspiring experience of survival, relapse and recovery in a family coping with addiction over many years.
- DirectorRick FamuyiwaStarsShameik MooreTony RevoloriKiersey ClemonsLife changes for Malcolm, a geek who's surviving life in a tough neighborhood, after a chance invitation to an underground party leads him and his friends into a Los Angeles adventure.
- DirectorRyan FleckStarsRyan GoslingAnthony MackieShareeka EppsAn inner-city junior high school teacher with a drug habit forms an unlikely friendship with one of his students after she discovers his secret.
- DirectorGlenn Gordon CaronStarsMichael KeatonKathy BakerMorgan FreemanA hustling drug addict checks himself into rehabilitation to escape trouble with the law and realizes that it's exactly what he needs.
- DirectorMichael CristoferStarsAngelina JolieFaye DunawayElizabeth MitchellThe story of the life of Gia Carangi, a top fashion model from the late 1970s, from her meteoric rise to the forefront of the modeling industry, to her untimely death.
- DirectorBetty ThomasStarsSandra BullockViggo MortensenDominic WestA big-city newspaper columnist is forced to enter a drug and alcohol rehab center after ruining her sister's wedding and crashing a stolen limousine.
- DirectorNeil ArmfieldStarsHeath LedgerAbbie CornishGeoffrey RushA poet falls in love with an art student who gravitates to his bohemian lifestyle -- and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.
- DirectorJustin KerriganStarsJohn SimmLorraine PilkingtonShaun ParkesFive youngsters embrace the 90s clubbing scene on a drug-fuelled weekend of partying in Cardiff.
- DirectorJoshua MarstonStarsCatalina Sandino MorenoGuilied LopezOrlando TobónA pregnant Colombian teenager becomes a drug mule to make some desperately-needed money for her family.
- DirectorMichael WinterbottomStarsSteve CooganLennie JamesJohn ThomsonIn 1976, Tony Wilson sets up Factory Records and brings Manchester's music to the world.
- DirectorVanessa PariseStarsBella ThorneDaniela BobadillaIsrael BroussardSweet suburban teen Amanda is introduced by her new friends to prescription drug-sharing, but the recreational fun soon leads her to a life-altering heroin addiction.
- DirectorRobert MandelStarsMia FarrowJulia WhelanCliff De YoungThe Secret Life of Zoey depicts the events that took place in Zoey Carter's life...
- DirectorBarbet SchroederStarsMickey RourkeFaye DunawayAlice KrigeBased on the life of successful poet Charles Bukowski and his exploits in Hollywood during the 60s, 70s, and 80s.
- DirectorPeter HedgesStarsJulia RobertsLucas HedgesCourtney B. VanceA drug addicted teenage boy shows up unexpectedly at his family's home on Christmas Eve.
- DirectorRoger CormanStarsPeter FondaSusan StrasbergBruce DernA disillusioned TV-commercial director is guided by his friend through an LSD trip, during which he evaluates his identity and his relationships with women.
- DirectorRichard RushStarsSusan StrasbergDean StockwellJack NicholsonA deaf runaway is taken in by a psychedelic band while searching for her missing brother in San Francisco's Haight-Ashbury hippie district.
- DirectorVondie Curtis-HallStarsTupac ShakurTim RothThandiwe NewtonTwo friends try to kick their drug addiction after a friend dies from an overdose, when they try to enroll in a detox program, things quickly go wrong.
- DirectorGregg ArakiStarsAnna FarisJohn KrasinskiAdam BrodyAfter a young actress unknowingly eats her roommate's marijuana cupcakes, her day becomes a series of misadventures.
- DirectorBlake EdwardsStarsJack LemmonLee RemickCharles BickfordAn alcoholic marries a young woman and systematically addicts her to booze so that they can share his "passion" together.