When violent conflict breaks out between greedy railroaders and a tribe of Mescalero Apaches, only two men, destined to be blood brothers, can prevent all-out war: chief's son Winnetou and German engineer Old Shatterhand.
Forester, a ruthless oil baron, wants to create a war between the native American tribes and the white men. Old Shatterhand, Winnetou and their sidekick Castlepool try to prevent this.
Rollins' gang wants to grab land by inciting the settlers in a war against the Indians but Winnetou and Old Shatterhand try to keep the peace, until Rollins frames Winnetou up for the murder of Jicarilla Chief's son.
In their first cinematic adventure, Apache chief Winnetou and mountain man Old Shatterhand pursue a gang of murderous outlaws who will stop at nothing to find the legendary treasure of Silver Lake.