- Once taught acting at a maximum-security prison.
- During her freshman year in college (at Stony Brook) she was crowned Miss New York. She was 19 at the time, the youngest woman ever to hold that title.
- She is also an author. Her first book, "The Girl Code: The Secret Language of Single Women (On Dating, Sex, Shopping and Honor Among Girlfriends)," was released on Valentine's Day 2001. She has also written for Jane, Esquire, Glamour, and Self magazines and is a regular monthly contributor to Cosmopolitan, Soma, and Gear.
- Half-Irish and half-Italian.
- After a breakup with her fiancé, Diane and a friend, an artist named Laura Bailey, started a greeting-card company called Other Announcements.
- While deciding on her major at New York's Stony Brook University, she took various theater classes. She then applied for a scholarship to a prestigious drama program at Loughborough University in England. She was accepted and studied classical theater there. She eventually graduated with a joint B.A. from the two universities.
- She was relieved to leave Rescue Me (2004) for Numb3rs (2005) after being away from her native Los Angeles home and for the physical demands of playing a New York City firefighter.
- She has been appointed as an ambassador to the Mineseeker Foundation and the Sole of Africa, a campaign dedicated to detecting and removing landmines in Africa. The Mineseeker Foundation's patrons have included Nelson Mandela, Sir Richard Branson, Queen Noor, and Brad Pitt.
- Pregnant with twins [April 21, 2008].
- She was a model at the age of 12.
- Close friends with NCIS (2003) star Pauley Perrette.
- She is producing Children of God: Lost and Found (2007), a forthcoming HBO documentary about the Children of God cult (also known as the Family of Love and The Family). It will examine the lives of several children who escaped from the cult and had to be reintroduced into mainstream society without money, education, or family support. Farr will produce and add artistic opinions.
- Diane and her husband, Seung Chung, became the parents of a boy, Beckett Mancuso Chung, on March 16, 2007, in Los Angeles. Beckett, named after Samuel Beckett, weighed in at 8 lb 2 oz and was 22 inches long.
- Engaged to Seung Yong Chung (as of October 29, 2005), whom she is set to marry June 24, 2006. Seung is a marketing executive. (May 2006)
- Appeared in two different TV series episodes with the same title, "By the Book": White Collar (2009) in 2010 and CSI: Miami (2002) in 2011.
- Has the same wedding anniversary as Numb3rs (2005) co-star Dylan Bruno: 24 June 2006.
- Born on exactly the same date as supermodel Angie Everhart.
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