- Ex-mother-In-law of Edith Frank (1900-1945).
- Great-Great-Grandmother of Hannah Milena Elias (1995-alive) and Leah Anouk Elias (1997-alive).
- Great-Grandmother of Patrick Elias (1966-alive) and Oliver Elias (1971-alive).
- Granddaughter of Emanuel Stern (1799-1841), Helena Stern (Schwarzschild) (1806-1886), Elkan Juda Cahn (1796-1884) and Betty Cahn (1805-1853).
- Grandmother of Stephan Elias (1921-1980),Buddy Elias (1925-2015,) Margot Frank (1926-1945) and Anne Frank (1929-1945).
- Sister-in-law of Rebekka Loewi (Frank) (1842-1928) Jakob Frank (1843-1878), Rosa (Rosalia) Loewi (Frank) (1844-1929), Sophie Frank (1846-1927); Veronika Frank (1849-1849); Arnold Frank (1850-1972); Leon Frank (1853-1915), Caroline Reinhard (Frank) (1854-1930) and Emil Frank (1857-1878).
- Niece of Bernhard Eduard Stern (b.1835), Julius Cahn (b.1830), Simon Wilhelm Emil Cahn (b.1825), Josephina Cahn (b.1829); Bertha Cahn (b.1830) and Charlotte Cahn (b.1827).
- Daughter-in-law of Zacharias Frank (1811-1884) and Barbara Babette Frank (Hammelstett) (1814-1891).
- Daughter of August Heinrich Stern (1838-1878) and Cornelia Elisabeth Stern (Cahn) (1840-1921).
- Step-grandmother of Heinz Geiringer (1926-1945) and Eva Schloss (b.1929).
- Half-niece of Siegmund Emanuel Stern (b.1830).
- Mother of Robert Frank (1886-1953),Otto Frank (1889-1980), Herbert Frank (1891-1987) and Helene Frank Elias (1893-1986).
- Mother-in-law of Elfriede Geiringer (1905 - 1998).
- After the unexpected death of Michael Frank in 1909, Alice took over the family business, supported by her now adult sons, Robert and Otto.
- When the First World War broke out in 1914, the Frank family's three sons all served as front-line soldiers in the German army. Alice and her daughter Leni worked as auxiliary nurses in a Red Cross military hospital. After the war, Otto Frank was awarded the Iron Cross for his military services. A considerable proportion of the family fortune was spent on purchasing war bonds. The family lost a significant part of its capital when Germany lost the war. The dire economic and political situation resulted in a constant downward spiral of the banking business, which was finally dissolved in early 1934.
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