Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "disease"
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51. Lorenzo's Oil (1992)
PG-13 | 129 min | Biography, Drama
Lorenzo Odone, a Virginia 5-year-old, develops a degenerative nerve disease so rare that nobody is working on a cure, so his parents decide to immerse themselves in research and tackle the problem themselves.
Director: George Miller | Stars: Nick Nolte, Susan Sarandon, Peter Ustinov, Kathleen Wilhoite
Votes: 24,147 | Gross: $7.29M
52. Mimic (1997)
R | 105 min | Horror, Sci-Fi
Three years ago, entomologist Dr. Susan Tyler genetically created an insect to kill cockroaches carrying a virulent disease. Now, the insects are out to destroy their only predator, mankind.
Director: Guillermo del Toro | Stars: Mira Sorvino, Jeremy Northam, Alexander Goodwin, Giancarlo Giannini
Votes: 55,853 | Gross: $25.48M
53. See You on Venus (2023)
94 min | Drama, Romance
An 18 year-old orphaned girl wants to travel to Europe to track down her biological mother, so when she meets a kind-hearted young man reeling from the guilt of a fatal accident, she convinces him to accompany her on the journey.
Director: Joaquín Llamas | Stars: Virginia Gardner, Alex Aiono, Rob Estes, Eowyn Nyby Krieger
Votes: 3,499
54. Cabin Fever (2002)
R | 93 min | Horror
Five college graduates rent a cabin in the woods and begin to fall victim to a horrifying flesh-eating virus, which attracts the unwanted attention of the homicidal locals.
Director: Eli Roth | Stars: Jordan Ladd, Rider Strong, James DeBello, Cerina Vincent
Votes: 83,910 | Gross: $21.16M
55. Splice (2009)
R | 104 min | Horror, Sci-Fi
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Director: Vincenzo Natali | Stars: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon
Votes: 101,933 | Gross: $17.00M
56. Exam (2009)
Not Rated | 101 min | Crime, Mystery, Thriller
Eight candidates for a highly desirable corporate job are locked together in an exam room and given a final test with just one seemingly simple question. However, it doesn't take long for confusion to ensue and tensions to unravel.
Director: Stuart Hazeldine | Stars: Adar Beck, Gemma Chan, Nathalie Cox, John Lloyd Fillingham
Votes: 125,890
57. The Girl with All the Gifts (2016)
R | 111 min | Action, Adventure, Drama
A scientist and a teacher living in a dystopian future embark on a journey of survival with a special young girl named Melanie.
Director: Colm McCarthy | Stars: Sennia Nanua, Fisayo Akinade, Dominique Tipper, Paddy Considine
Votes: 64,611
58. Leviathan (1989)
R | 98 min | Adventure, Horror, Mystery
Perched on the hull of a wrecked Soviet freighter, a team of deep-sea miners led by head oceanographer Steven Beck comes face to face with a mutant creature that's the product of a failed genetic experiment.
Director: George P. Cosmatos | Stars: Peter Weller, Richard Crenna, Amanda Pays, Daniel Stern
Votes: 23,919 | Gross: $15.70M
59. Æon Flux (2005)
PG-13 | 93 min | Action, Adventure, Sci-Fi
Æon Flux is a mysterious assassin working for the Monicans, a group of rebels trying to overthrow the government. When she is sent on a mission to kill the Chairman, a whole new mystery is found.
Director: Karyn Kusama | Stars: Charlize Theron, Frances McDormand, Sophie Okonedo, Marton Csokas
Votes: 132,971 | Gross: $25.87M
60. The Last of Us (2013 Video Game)
M | Action, Adventure, Drama
In a hostile, post-pandemic world, Joel and Ellie, brought together by desperate circumstances, must rely on each other to survive a brutal journey across what remains of the United States.
Directors: Neil Druckmann, Bruce Straley | Stars: Troy Baker, Ashley Johnson, Hana Hayes, Jeffrey Pierce
Votes: 76,447
61. The Crazies (2010)
R | 101 min | Horror
After a strange and insecure plane crash, an unusual toxic virus enters a quaint farming town. A young couple are quarantined, but they fight for survival along with help from a couple of people.
Director: Breck Eisner | Stars: Radha Mitchell, Timothy Olyphant, Danielle Panabaker, Joe Anderson
Votes: 129,237 | Gross: $39.12M
62. eXistenZ (1999)
R | 97 min | Horror, Mystery, Sci-Fi
A game designer on the run from assassins must play her latest virtual reality creation with a marketing trainee to determine if the game has been damaged.
Director: David Cronenberg | Stars: Jude Law, Jennifer Jason Leigh, Ian Holm, Willem Dafoe
Votes: 107,455 | Gross: $2.84M
63. Outbreak (1995)
R | 127 min | Action, Drama, Thriller
Army doctors struggle to find a cure for a deadly virus spreading throughout a California town that was brought to America by an African monkey.
Director: Wolfgang Petersen | Stars: Dustin Hoffman, Rene Russo, Morgan Freeman, Kevin Spacey
Votes: 138,119 | Gross: $67.82M
64. A Prophet (2009)
R | 155 min | Crime, Drama
A delinquent Muslim man struggles to get by in prison until he is taken under the wing of a powerful mob boss. But his gradual rise through the mob's ranks brings him in conflict with his mentor.
Director: Jacques Audiard | Stars: Tahar Rahim, Niels Arestrup, Adel Bencherif, Reda Kateb
Votes: 102,362 | Gross: $2.08M
65. Midnight Sun (2018)
PG-13 | 91 min | Drama, Romance
A 17-year-old girl suffers from a condition that prevents her from being out in the sunlight.
Director: Scott Speer | Stars: Bella Thorne, Patrick Schwarzenegger, Rob Riggle, Quinn Shephard
Votes: 36,278 | Gross: $9.56M
66. Miracles from Heaven (2016)
PG | 109 min | Biography, Drama, Family
Based on the incredible true story of the Beam family.
Director: Patricia Riggen | Stars: Jennifer Garner, Kylie Rogers, Martin Henderson, Brighton Sharbino
Votes: 28,513 | Gross: $61.71M
67. Dreamcatcher (2003)
R | 134 min | Drama, Horror, Sci-Fi
Friends on a camping trip discover that the town they're vacationing in is being plagued in an unusual fashion by parasitic aliens from outer space.
Director: Lawrence Kasdan | Stars: Morgan Freeman, Thomas Jane, Jason Lee, Damian Lewis
Votes: 96,601 | Gross: $33.72M
68. Resident Evil: The Final Chapter (2016)
R | 107 min | Action, Horror, Sci-Fi
Alice returns to where the nightmare began: The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Iain Glen, Ali Larter, Shawn Roberts
Votes: 101,266 | Gross: $26.83M
69. Thirst (2009)
R | 134 min | Drama, Fantasy, Horror
Through a failed medical experiment, a priest is stricken with vampirism and is forced to abandon his ascetic ways.
Director: Park Chan-wook | Stars: Song Kang-ho, Kim Ok-bin, Choi Hee-jin, Seo Dong-soo
Votes: 51,529 | Gross: $0.30M
70. Rose Red (2002)
PG-13 | 85 min | Horror, Mystery, Thriller
A college professor and a team of psychics investigate mysterious deaths and disappearances at an old abandoned mansion.
Stars: Nancy Travis, Matt Keeslar, Kimberly J. Brown, David Dukes
Votes: 27,102
71. Everything, Everything (2017)
PG-13 | 96 min | Drama, Romance
A teenager who's spent her whole life confined to her home falls for the boy next door.
Director: Stella Meghie | Stars: Amandla Stenberg, Nick Robinson, Anika Noni Rose, Ana de la Reguera
Votes: 42,597 | Gross: $34.00M
72. Osmosis Jones (2001)
PG | 95 min | Animation, Action, Adventure
A policeman white blood cell, with the help of a cold pill, must stop a deadly virus from destroying the human they live in, Frank.
Directors: Bobby Farrelly, Peter Farrelly | Stars: Laurence Fishburne, Chris Rock, David Hyde Pierce, Brandy Norwood
Votes: 38,867 | Gross: $13.60M
73. Arctic Circle (2018– )
TV-MA | 50 min | Crime, Drama, Thriller
A detective and a virologist pursue an unusual investigation that places them on the wrong side of the law.
Stars: Iina Kuustonen, Pihla Viitala, Venla Ronkainen, Mikko Leppilampi
Votes: 2,841
74. Eli (I) (2019)
R | 98 min | Drama, Horror, Mystery
A boy receiving treatment for his auto-immune disorder discovers that the house he's living in isn't as safe as he thought.
Director: Ciarán Foy | Stars: Charlie Shotwell, Kelly Reilly, Max Martini, Lili Taylor
Votes: 41,002
75. Resident Evil: Retribution (2012)
R | 95 min | Action, Horror, Sci-Fi
Alice fights alongside a resistance movement to regain her freedom from an Umbrella Corporation testing facility.
Director: Paul W.S. Anderson | Stars: Milla Jovovich, Sienna Guillory, Michelle Rodriguez, Aryana Engineer
Votes: 150,468 | Gross: $42.35M
76. Cat on a Hot Tin Roof (1958)
Not Rated | 108 min | Drama
Brick is an alcoholic ex-football player who drinks his days away and resists the affections of his wife. A reunion with his terminal father jogs a host of memories and revelations for both father and son.
Director: Richard Brooks | Stars: Elizabeth Taylor, Paul Newman, Burl Ives, Jack Carson
Votes: 53,531 | Gross: $17.57M
77. The Andromeda Strain (1971)
G | 131 min | Mystery, Sci-Fi, Thriller
Top scientists work feverishly in a secret, state-of-the-art laboratory to discover what killed the citizens of a small town and how the deadly contagion can be stopped.
Director: Robert Wise | Stars: James Olson, Arthur Hill, David Wayne, Kate Reid
Votes: 40,551 | Gross: $3.42M
78. The Omega Man (1971)
PG | 98 min | Action, Drama, Sci-Fi
Dr Robert Neville has developed an experimental vaccine which makes him the only immune survivor of a biological catastrophe. A gang of homicidal mutants blame science for their condition and attempt to kill him.
Director: Boris Sagal | Stars: Charlton Heston, Anthony Zerbe, Rosalind Cash, Paul Koslo
Votes: 34,132 | Gross: $8.72M
79. The Division (I)
Action, Sci-Fi, Thriller | Announced
In the near future, a pandemic virus is spread via paper money on Black Friday, decimating New York. A group of civilians, trained to operate in catastrophic times, are activated in an attempt to save who and what remains.
Director: Rawson Marshall Thurber | Stars: Jake Gyllenhaal, Jessica Chastain, McKinley Stamper
80. Shivers (1975)
R | 87 min | Horror, Sci-Fi
The residents of a suburban high-rise apartment building are being infected by a strain of parasites that turn them into mindless, sex-crazed fiends out to infect others by the slightest sexual contact.
Director: David Cronenberg | Stars: Paul Hampton, Joe Silver, Lynn Lowry, Allan Kolman
Votes: 23,672
81. Balto (1995)
G | 78 min | Animation, Adventure, Drama
An outcast Husky risks his life with other sled dogs to prevent a deadly epidemic from ravaging Nome, Alaska.
Director: Simon Wells | Stars: Kevin Bacon, Bob Hoskins, Bridget Fonda, Jim Cummings
Votes: 48,253 | Gross: $11.35M
82. Phenomenon (1996)
PG | 123 min | Drama, Fantasy, Romance
An ordinary man sees a bright light descend from the sky, and discovers he now has super-intelligence and telekinesis.
Director: Jon Turteltaub | Stars: John Travolta, Kyra Sedgwick, Forest Whitaker, Robert Duvall
Votes: 83,952 | Gross: $104.64M
83. The Wolfman (2010)
R | 103 min | Drama, Fantasy, Horror
Upon his return to his ancestral homeland, an American man is bitten and subsequently cursed by a werewolf.
Director: Joe Johnston | Stars: Benicio Del Toro, Anthony Hopkins, Emily Blunt, Simon Merrells
Votes: 111,869 | Gross: $61.98M
84. Night of the Living Dead (1990)
R | 92 min | Horror
When the unburied dead return to life and seek human victims, seven refugees shelter in a house in the Pennsylvanian countryside.
Director: Tom Savini | Stars: Tony Todd, Patricia Tallman, Tom Towles, McKee Anderson
Votes: 45,630 | Gross: $5.84M
85. The Darkest Minds (2018)
PG-13 | 104 min | Action, Adventure, Drama
After a disease kills 98% of children, the survivors develop powers and are declared a threat. 16-year-old Ruby, escapes the government facility and joins a group of rebel teenagers ready to fight the government forces out to get them.
Director: Jennifer Yuh Nelson | Stars: Amandla Stenberg, Mandy Moore, Bradley Whitford, Harris Dickinson
Votes: 36,169 | Gross: $12.70M
86. The Normal Heart (2014 TV Movie)
TV-MA | 132 min | Biography, Drama, History
In the early 1980s, the onset of the HIV-AIDS crisis in New York led to an emergence of homosexual activists. With support from the medical community, they try to raise awareness about the disease.
Director: Ryan Murphy | Stars: Mark Ruffalo, Jonathan Groff, Frank De Julio, William DeMeritt
Votes: 37,847
87. Dangerous Beauty (1998)
R | 111 min | Biography, Drama, Romance
A Venetian courtesan becomes a hero to her city, but later becomes the target of an inquisition by the Church for witchcraft.
Director: Marshall Herskovitz | Stars: Catherine McCormack, Rufus Sewell, Oliver Platt, Fred Ward
Votes: 19,680 | Gross: $4.53M
88. Patient Zero (I) (2018)
R | 93 min | Action, Drama, Horror
After an unprecedented global pandemic turns the majority of humankind into violent "Infected," a man gifted with the ability to speak the Infected's new language leads the last survivors on a hunt for Patient Zero and a cure.
Director: Stefan Ruzowitzky | Stars: Matt Smith, Natalie Dormer, John Bradley, Clive Standen
Votes: 9,991
89. The Cure (1995)
PG-13 | 97 min | Adventure, Drama
Erik, a loner, finds a friend in Dexter, an eleven-year-old boy with AIDS. They vow to find a cure for AIDS together and save Dexter's life in an eventful summer.
Director: Peter Horton | Stars: Joseph Mazzello, Brad Renfro, Aeryk Egan, Delphine French
Votes: 10,719 | Gross: $2.57M
90. The Bay (II) (2012)
R | 85 min | Horror, Sci-Fi, Thriller
Chaos breaks out in a small Maryland town after an ecological disaster occurs.
Director: Barry Levinson | Stars: Will Rogers, Kristen Connolly, Kether Donohue, Frank Deal
Votes: 29,735 | Gross: $0.03M
91. The Painted Veil (2006)
PG-13 | 125 min | Drama, Romance
Dr Walter gets married to the beautiful Kitty but soon finds out that she is cheating on him. Battling his way through problems, he heads to China to fight a dreaded disease spread in a small village.
Director: John Curran | Stars: Naomi Watts, Edward Norton, Liev Schreiber, Catherine An
Votes: 96,056 | Gross: $8.06M
92. Andrei Rublev (1966)
R | 189 min | Biography, Drama, History
The life, times and afflictions of the fifteenth-century Russian iconographer St. Andrei Rublev.
Director: Andrei Tarkovsky | Stars: Anatoliy Solonitsyn, Ivan Lapikov, Nikolay Grinko, Nikolay Sergeev
Votes: 57,188 | Gross: $0.10M
93. The Madness of King George (1994)
PG-13 | 110 min | Biography, Comedy, Drama
When King George III goes mad, his Lieutenants try to adjust the rules to run the country without his participation.
Director: Nicholas Hytner | Stars: Nigel Hawthorne, Helen Mirren, Rupert Graves, Amanda Donohoe
Votes: 18,465 | Gross: $15.24M
94. Ultraviolet (2006)
PG-13 | 88 min | Action, Sci-Fi
A beautiful haemophage infected with a virus that gives her superhuman powers has to protect a boy in a futuristic world, who is thought to be carrying antigens that would destroy all hæmophages.
Director: Kurt Wimmer | Stars: Milla Jovovich, Cameron Bright, Nick Chinlund, Sebastien Andrieu
Votes: 84,158 | Gross: $18.50M
95. Viral (I) (2016)
R | 85 min | Drama, Horror, Sci-Fi
Following the outbreak of a virus that wipes out the majority of the human population, a young woman documents her family's new life in quarantine and tries to protect her infected sister.
Directors: Henry Joost, Ariel Schulman | Stars: Sofia Black-D'Elia, Lio Tipton, Travis Tope, Michael Kelly
Votes: 9,770
96. House of Usher (1960)
Approved | 79 min | Drama, Horror
Upon entering his fiancée's family mansion, a man discovers a savage family curse and fears that his future brother-in-law has entombed his bride-to-be prematurely.
Director: Roger Corman | Stars: Vincent Price, Mark Damon, Myrna Fahey, Harry Ellerbe
Votes: 15,537 | Gross: $3.16M
97. The Roman Spring of Mrs. Stone (2003 TV Movie)
R | 114 min | Drama, Romance
A failing star is faced with a lifestyle change when her rich husband suddenly dies while they are en route to Italy. She then sets off in a series of flings with gigolos found for her by ... See full summary »
Director: Robert Allan Ackerman | Stars: Helen Mirren, Olivier Martinez, Anne Bancroft, Rodrigo Santoro
Votes: 1,784
98. Blindness (2008)
R | 121 min | Drama, Mystery, Thriller
A city is ravaged by an epidemic of instant white blindness.
Director: Fernando Meirelles | Stars: Julianne Moore, Mark Ruffalo, Gael García Bernal, Yûsuke Iseya
Votes: 75,264 | Gross: $3.07M
99. Last Holiday (2006)
PG-13 | 112 min | Comedy, Drama, Romance
Upon learning of a terminal illness, a shy woman decides to sell all her possessions and live it up at a posh Central European hotel.
Director: Wayne Wang | Stars: Queen Latifah, LL Cool J, Timothy Hutton, Giancarlo Esposito
Votes: 36,352 | Gross: $38.36M
100. Cowboy Bebop: The Movie (2001)
TV-14 | 115 min | Animation, Action, Crime
A terrorist explosion releases a deadly virus on the masses, and it's up to the bounty-hunting Bebop crew to catch the cold-blooded culprit.
Directors: Shin'ichirô Watanabe, Mary Elizabeth McGlynn, Tensai Okamura, Hiroyuki Okiura, Yoshiyuki Takei | Stars: Beau Billingslea, Melissa Fahn, Nicholas Guest, Kôichi Yamadera
Votes: 53,347 | Gross: $1.00M