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- Harvey Keitel plays Penfield Gruber, a once great scientist, reduced to managing a sleazy hotel. Gruber monitors the daily comings and goings of his tenants, mainly for his own interest, until underworld figures ask him to spy on a suspected double-crosser. While watching the man, Gruber overhears a murder plot.
- John Lithgow stars and Ralph Macchio co-stars as his son. Their uneasy reunion accidentally sparks war-haunted violence, and they share a harrowing fight for survival that will either destroy them or unify them forever.
- A Roger Corman tale of Dr. James Xavier's devastating experiments on himself and the unforeseen.