The film is ostensibly an adaptation of the 1928 novel "The Well of Loneliness", by British author Radclyffe Hall. Centering on a lesbian woman's struggle to find a place in the world, the novel is considered one of the first serious works of fiction on the subject of homosexuality.
Also released under the titles "Children of Loneliness" and "The Un-natural Sin". A 1937 newspaper ad for the latter title called it "The 'Queerest' Picture Ever Made" and promised the audience sensationalism in the form of "Daughters of Lesbia", "Phallic Worshippers", and "Homosexuals & Perverts".
This film is presumed lost.