An old flame from Arch's past provides Harry with legal advice regarding a doctor who knowingly exposed a patient to a fatal virus for the sake of performing a ground breaking trans-species organ transplant.
Repeat medivac flights to a farm lead doctors to suspect that the workers are intentionally electrocuting themselves in an attempt to cure their illnesses.
Harry is confronted by an old war buddy and his decision to tell the press about an off-duty killing they were involved in during their time in Vietnam.
Harry's conscience is questioned after a fatal fire at a rental building he owns burns down. Arch and Bree find a young pregnant woman still alive in the burning rubble of the building.
Medical practices in the ER are publicly criticised by Bethlehem West neurosurgeon Dr. David Delamere, resulting in Arch being investigated on a charge of manslaughter relating to the death of one of his patients.
Arch comes to the aid of an aboriginal man who has a heart attack, the same man responsible for spearing an art dealer brought into the hospital earlier.
After robbing Wayne's bank, a young Bonnie and Clyde couple, Armalite and Shaneen, crash their car and Armalite's head is pierced by a length of rebar.
The Emergency department is quarantined when Nikki's blood tests show a strange antibody that may be a mutated rabbit calicivirus. While Tom and Arch search for answers, Nikki takes a turn for the worse.
An old friend of Julia's, Dr. Cliff Haughton, is suspected of causing a car accident and is attacked in the ER by the girlfriend of a man who died in the accident.
Tom forges the organ donation papers of a deceased patient whose mother is vehemently opposed to it, and then pays off the woman so that she won't sue the hospital.
Marina spends the night at Dave's place. She tells Dave she's thinking about leaving her Religious Order. Unsure what to do next and unable to stay at the Sister's house, she turns to Arch for support.