Only three nephews appear here, instead of four.
One of the few times Bluto/Brutus is shown smoking.
Television (and the curious looking antennas it necessitated for reception) was slowly becoming part of American home life, even in the far away, wild west, as shown here.
The title is a play on the popular media cowboy, Hopalong Cassidy.
The saguaro cactus in the background would indicate the ranch was located in the Sonoran Desert, which spans the Southwest regions of the U.S. and Mexico. Although most cattle ranch stories are set in nearby Texas, there are some in The Grand Canyon State as well.