This is an interesting show, that uses characters within several different massively multiplayer online role-playing games like the very popular Everquest to more obscure ones like Second Life... it is very much like a moving comic book, where heroes are somewhat larger than life, and villians are pretty much irredeemable. At times, information about new games or hints for players in current games are presented in an entertaining way.
The show is very much like a British comedy to Americans... either people love it or hate it. It is a very original idea, however budget constraints from the growing G4 cable network makes the central location where host Dave Meinstein performs (called "The Hub") looks like something that could have been on Mystery Science Theater 3000.
If you are willing to try something with a original premise and a somewhat quirky sense of humor, then check out Portal... if more traditional shows like Friends or Everyone Loves Raymond are your style, you may miss the humor that this show presents.