The original title of this episode was "Flight Monster Blood". However, shortly before it aired, it was changed to "More Monster Blood".
The shot of the overweight man's glasses lying broken on the floor is a reference to the cover of the first Monster Blood novel, which was also that of the Monster Blood DVD. which this also appeared on.
This episode is not based on one of R.L. Stine's novels and was made just for television, though it borrows some elements from the novel Monster Blood II (the character of Conan, for instance).