Just before Cameron walks in, Chase finishes a joke that he's telling Foreman. "And he wipes himself with the rabbit." Eddie Murphy told this joke: A bear asks a rabbit if he has a problem with poop sticking to his fur. The rabbit says no. So, the bear wipes himself with the rabbit.
Jon Cho plays a 21-year-old patient; when this episode was filmed, the actor was 34.
Elizabeth Sung previously played John Cho's mother on episode "Dead Man Dating" from Charmed season 1.
Cameron jokingly calls Chase Sherlock. House is loosely based on Sherlock Holmes.
Wilson states that House hasn't dated since Disco died. He should know: Robert Sean Leonard appeared in The Last Days of Disco (1998).