- Beatrice Carver: [to her daughter] Someday you're gonna have a baby and you're gonna feel overwhelmed by this little life that you're responsible for and you're gonna think that everything you do is wrong, and that's normal. You're gonna obsess about what to feed it and where to send it to school and whether it should take violin or piano. But I'm gonna let you in on a little secret: it doesn't matter. Whether your kid is a concert pianist or a math genius it just doesn't matter, because at the end of the day all that matters is if your kid is happy.
- Dr. Meredith Grey: So go ahead... argue with the refs. Change the rules. Cheat a little. Take a break and tend to your wounds... but play. Play. Play hard, play fast, play loose and free. Play as if there's no tomorrow. It's not whether you win or lose, it's how you play the game.
- Dr. Isobel "Izzie" Stevens: He's just not George anymore. He's broken George. First he chops off his hair, then he starts hanging out with this Callie. What is-that's not a name Callie. Who is she anyway? I'm his best friend, not that he talks to me anymore.
- Denny Duquette: Triple word score, 69 points. Woman, I'm beating the pants off you. Pay attention, what the hell are you doing?
- Dr. Isobel "Izzie" Stevens: I'm knitting a sweater. Actually Meredith, that's my friend - the friend that broke George - is knitting a sweater. She's not really knitting a sweater because she can not knit but I want her to think she is knitting a sweater because she and I took a celibacy vow so she's replacing sex with knitting and so I'm knitting pieces of Meredith's sweater so that I can switch them out with hers so that she can really believe she's knitting because if anybody needs to be celibate, it's Meredith because she broke George.
- Denny Duquette: You took a vow of celibacy?
- Dr. Isobel "Izzie" Stevens: So George... he's really, really your type, huh?
- Dr. Callie Torres: You don't see him
- [pause]
- Dr. Callie Torres: Either of you. You don't see him. He's just... He's just George to you. He's... He's just O'Malley. Your roommate...
- Dr. Isobel "Izzie" Stevens: You don't have to get all up...
- Dr. Callie Torres: He makes my world stop. George O'Malley is sweet and kind and smart and strong and he makes my world stop. So you shut up about him.
- Dr. Callie Torres: [Turns to Meridith, who's taking out her anger on a removed plaster leg cast] Don't forget to clean it up. When you've finished smashing.
- [Leaves room]
- Dr. Isobel "Izzie" Stevens: [Turning to Meredith] Holy Crap! George is her McDreamy!