Trevor Moore actually drank whiskey for the "Whiskey Supersize" sketch. After a few takes he eventually had to switch to warm iced tea.
In the "cubicle Boss" Sktech, Sam Brown drew his "painting" with a lighter colored marker then covered over it so that there wasn't an continuity. If you look closely you can see the outlines.
Some of the original lines in 'Sexy Fawn' were written out as it was deemed "too crude".
The drug dealer in the 'Dime Bag' sketch is actually the bouncer at 'Piano's', a club in New York City where the troupe often performs live shows.