Jeremy Kyle refused to appear on the show after his car was involved in an accident on the A1. This was because the show airs at the same time as his.
The air ambulance dispatcher Chris Solomons suffered from a heart attack whilst filming. He was revived with CPR and a defibrillator. This was shown later in the series and is widely used in training.
Celebrities such as Prince Andrew, James May, Gordon Ramsay and cricketer Ian Botham appeared on the show.
Richard Hammond presented the first series of the show after he was flown to the Leeds General Infirmary after a near-fatal jet engine car crashed at Elvington Airfield near York.
All of the film is edited in the Leeds Bradford hangar where the Air Ambulance is based.