- At a renaissance festival, a knight fights for the "queen's" hand. He falls to the ground with red eyes but no wounds. Wilson dates his first ex-wife. House and Thirteen dress up to investigate at the renaissance festival.
- House and the team take on the case of Sir William, a "knight" in a closed-off community of men and women living according to the ideals of the High Renaissance. As the team searches the medieval village for environmental factors contributing to Sir William's rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty, especially in regard to the "queen" of the community, one of Sir William's most frequent visitors. Meanwhile, Wilson starts over with an ex.—FOX Publicity
- Open at what appears to be a renaissance fair of some sort. Two men dressed as knights have a sword battle that ends with the smaller man the victory. While celebrating he falls backwards and we see that his eyes are completely red.
A nude House (Hugh Laurie) runs into Wilson's ex-wife Sam (Cynthia Watros) the morning after she has spent the night. House makes reference to not having heard she was in Wilson's life.
While the team discusses possible cases to take, House walks in swinging a sword. He tells them about the knight in their ER, who is part of a group of re-enactors who spend their weekends living that time period. He had been living there for a month straight. They go after the possibilities of both hematoma and allergic reaction.
House talks to Wilson (Robert Sean Leonard) and figures out Sam is Wilson's ex. House doesn't think she'll be any different than the woman he divorced.
During the knight's (William) MRI, he tells Chase (Jesse Spencer) and Taub (Peter Jacobson) that he takes the code of the knights very seriously throughout his entire life. William (Noah Segan) then starts vomiting.
Thirteen (Olivia Wilde) and Foreman (Omar Epps) take samples at the fairgrounds. They talk with two of the other re-enactors and find out William vomited before his sword fight after eating a cow's eye. Apparently the "king" was fond of making his knights eat gross-out stuff.
After an injection of epinephrine William's heart rate becomes irregular. When Thirteen goes to shock him we see he has a rash all over his chest.
Thirteen suggests it could be a MERSA infection. House orders a sample to confirm.
House talks to Cuddy (Lisa Edelstein) about Wilson dating Sam. House remembers how devastated Wilson was after Sam dumped him the first time and wants Cuddy to break them up somehow.
William sends his female friend (Shannon, the "queen") out of the room so he can tell Thirteen how bad his chest feels. She gets William to admit he's in love with Shannon (Sarah Jones), who is engaged to the king. Thirteen thinks he should tell Shannon how he feels. William doesn't think that's what knights do. The rash has spread to his back.
In the lab the guys learn William's infection is not MERSA. House walks in and shows them he has poison ivy from the handles of William's sword.
The team gets beeped that Williams's heart rate is slowing. Chase pushes epinephrine which seems to stabilize him.
House thinks there must be an environmental cause they've missed.
Wilson tells House that Sam wants to get to know him better. She thinks Wilson was hiding her. Wilson says he doesn't need any help and tells him to be his "usual selfish self."
Based on another conversation, Thirteen really thinks William should go after Shannon.
House shows up to dinner with a date that appears to be a transvestite prostitute.
Thirteen has ruled out Trichinosis, House's most recent theory. Foreman suggests re-testing samples to look for fungus.
House is upset his date and Sam are hitting it off.
William's legs start burning and turn purple. A grouchy House suggests they check William's apartment.
Wilson asks Cuddy whether she thinks he's making a mistake. Her response isn't overwhelmingly positive.
Taub and Foreman look at non-cancerous tumors from one of William's liver samples in a microscope. They are unsure what they are viewing.
At William's apartment they find a locked room dedicated to witchcraft.
House suggests the tumors are related to lead poisoning.
Wilson and Sam start fooling around and are interrupted by the sounds of House making dinner. He apologizes for dinner and they have a great meal. When Wilson leaves for the bathroom, House tells Sam he's not going to let her devastate him again and they share their mutual hatred.
With no lead present in William's tests, House and Thirteen dress up in period garb and return to the fairgrounds. In the apothecary shop, House discovers hemlock is being sold. The man says the only person he sold it to was the king (Miles).
Miles (Wes Ramsey) comes to the hospital and House confronts him about the hemlock. Miles says he has no idea what happened and just bought the "wild carrots" for the knights challenge.
William tells House that Miles wouldn't lie. Despite the charcoal treatment, he is still getting worse. Though there is hemlock in his blood, it's is not what is killing William.
House has Lucas (Michael Weston) do some digging on Sam. As Lucas explains he has not looked at her psychiatrist's report, Sam shows up at House's office. Sam says both of them care about Wilson and she wants him to give the couple a chance to find out if the relationship might work.
While holding the sword, House figures out the lesions on Williams's liver are the result of steroid use. Thirteen again suggests William tell Shannon how he feels. He thinks she deserves the best, which is the more successful Miles.
House decides against looking at Sam's confidential file.
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