During the flashback scene telling how Lois got involved in the porn industry, which is identified as taking place in the early 1980s, young Lois mentions being in debt because she maxed out her credit card buying a copy of E.T. the Extra-Terrestrial (1982) at the local video store. However, while released in 1982, the classic Steven Spielberg film did not receive a home video release until late 1988, and its retail price was only $24.95, which would hardly have put anyone into debt.
Stewie worries that he is a "porn baby", conceived during Lois's participation in a porn film while she was in college. This fear is furthered when he sees the actor playing the pizza delivery guy enter a scene, and that actor looks just like an adult version of Stewie. But this is impossible; Stewie is the youngest of the Griffin children; he would had to have been conceived after Lois was already married to Peter for several years, and had already had Meg and Chris, not while she was in college making a porn film.
When Lois returns to church to defend 'doing a porno' she refers to Jesus Christ hanging around with sinners, including Mary Magdalene, who she describes as a prostitute. There is no evidence in the bible that Mary Magdalene was a prostitute. She is often confused with the unnamed woman who is found in an act of adultery and, whom Jesus defends by asking anyone who is without sin to cast the first stone.