When Lizzie Sparks and Rossi are talking about autism, she says, "It sounds like you speak from experience." Joe Mantegna, who plays Rossi, has an autistic daughter.
This marks the first time a non-cast member says the bookend quote, in this case, Ian Doyle (Timothy V. Murphy).
Mimi Kennedy (Miss Rogers) was in Dharma & Greg (1997) with Thomas Gibson (Hotch). She played his wife's mother.
When Garcia is talking moving so fast that the earth's rotation would reverse and cause time to rewind, her bib almost forms a pentagon. This is the same shape as the Superman symbol and a most likely a reference to the 1978 film.