Audrey keeps reliving the same day in an attempt to save lives. Jason Priestley was a recurring character on the series Tru Calling, about a woman who relived days in order to save lives.
When Audrey calls Duke at The Grey Gull, the camera briefly shows a radio with a CD in it. The CD is "The Downward Spiral" by Nine Inch Nails.
When Audrey runs down the street, 36:15 minutes into the episode, she runs past a store flying the rainbow Pride flag.
In the previous episode, Roots, Vince asks Nathan to follow him on Twitter. In this episode, there is a callback to this with a poster on the back wall of the classroom asking people to follow @vincehaven on Twitter.
Nathan mentions that Audrey is stuck in his 2nd favourite Bill Murray movie. The movie he is referring to is Groundhog Day (1993).