Scott Wilson had the idea to carry a medical bag when a few of the group members were clearing out the prison.
This is actress Danai Gurira's first time on screen as Michonne. The character of Michonne was introduced at the end of the season 2 finale, Beside the Dying Fire (2012), but Gurira didn't portray her as she hadn't been cast at the time. An extra filled in for the spot of Michonne in that episode.
This episode begins the Safety Behind Bars story arc from the comics.
When Carl enters the kitchen of the house they scavenge the house, you can see a can of SMEAT on the counter, this is the same word they used on Waterworld when they showed the can of supposed 'spam'
The group is moving as a unit, showing they are a team and no longer broken.