Josh Keaton, the voice of Spider-Man on The Spectacular Spider-Man (2008), had originally recorded lines for this episode and previous episodes. However he was re-dubbed by Drake Bell for undisclosed reasons.
Galactus's heralds were energy constructs in this episode, but in the comics the Heralds had been real beings given Cosmic Powers by Galactus Air Walker and Firelord were Xandarians and Members of the Nova Corp prior to their service to Galactus. Terrax was a Birjan tyrant. Stardust was an Ethereal, but she did not have water based powers in the comics