The episode is dedicated to actor Lance Reddick (Zeus), who passed away in 2023 shortly after production wrapped.
This would be one of Lance Reddick's final roles.
After getting his searchers license Grover states that he will be looking outside the usual places that have been searched time and again for the missing god Pan, and that he is headed to the sea. This is an Easter egg for their season 2 adventure in The Sea of Monsters.
The title of this episode comes from chapter 22, which is the last chapter of the Lightning Thief novel.
In a flashback scene Luke tells Percy about how Annabeth is scared of spiders. This is due to the events of the story of Arachne and how she lost a competition with Athena and was turned into the first spider for her pride. In the novel we first learn about this fear when she and Percy are attacked by mechanical spiders while at Water World