A series first, the storyline does not feature a single appearance - or even mention - of Rick.
In the opening scene, a ship shaped like a calculator is firing on Alphabetrium. The calculator has 58008 written on its display. When you see this number upside down, it spells "BOOBS". Previously one of Rick's passwords for his clone families was the same number in the right order: "Eight zero zero eight five."
One of the main characters is Ice-T; oddly enough, Ice-T stars in this episode, but he doesn't voice the eponymous character but his father, Magma-Q (while the Ice-T character is played by Dan Harmon).
Oxygen-S/Infinity is voiced by Peter Serafinowicz, who previously played the foreign secret service director who sent Jaguar to kill Pickle Rick in Pickle Rick (2017).
The lowest rated episode in the show's history.