Lilly Tomlin continues her voice role of Miss Frizzle, but now under the name Professer Frizzle, while her younger sister continues to teach the class.
This version of the theme song is sung by Lin-Manuel Miranda.
In the original show, Ms. Frizzle's whole dress would change each episode to reflect it's current theme. In this one, only the new Frizzle's skirt and necklace would change and her blue shirt would stay the same.
Jyoti is the reboot's newcomer.