The Hybrid Monster was performance captured by actor Elias Toufexis who played the character of Kenzo in season 1. The producers and VFX team knew that Toufexis had an extensive background in Performance Capture and asked him to play the Hybrid.
In one of the final scenes aboard the UN ship at Venus there is a cameo appearance by Adam Savage from MythBusters (2003) as a member of the crew.
The title of the episode, Caliban's War, is also the title of Book 2 in The Expanse series, of which the latter half of season 2 is based.