Vivian Nixon and Norman Nixon Jr., who appear as interns in this episode, are the children of Debbie Allen, who plays Dr. Catherine Avery.
The title of this episode "What's Inside" is named after a song of the same name from Sara Bareilles' Broadway musical, Waitress.
During the first surgery in the episode, the song "Effortless" by swedish singer Sabina Ddumba can be heard.