Final appearance of Jeff Hephner as Jeff Clarke. He obtained a match for a hospital in Honolulu. The character first appeared in 2013 in A Problem House (2013) as a firefighter. His was the only character to transition from one "Chicago" series to another.
This episode is directed by Eriq La Salle. He played Dr. Peter Benton in another Chicago based series, ER. ER (1994).
The average lifespan from the time of diagnosis for an ALS patient is 3-5 years, but that largely depends on where the ALS sets in first; those with Bobar onset ALS have the shortest lifespan as it starts in the diaphragm.
In this episode, Sharon Goodwin reveals to a newly diagnosed patient that she too is diabetic. S. Epatha Merkerson is also diabetic in real life and was first found out that she had the condition in 2003.