Shakira teased the song hours prior its release sending personalized postcards to a few fans, where she appears climbing a tree. She stated in them: "I'm very happy to share with all of you my new single 'Me enamoré.' This song narrates a moment in my life when I was so in love that I was literally climbing trees".
"Me Enamoré" tells the story of when Shakira fell in love with her current partner Gerard Piqué, whom she met in 2010 on the set of the music video for "Waka Waka (This Time For Africa)", the official song of the 2010 FIFA World Cup.
In France, "Me Enamoré" debuted at number 72 on 14 April 2017, reaching number 41 after the release of its music video and eventually peaking at number 13 after the release of El Dorado.
The "Me Enamoré" official lyric video was released via Shakira's Vevo the day of the release of the song. Directed by James Zwadlo, it features the Spanish-language words along watercolor painted images, presumably for the non-Spanish speaking people to understand the song.
The music video was shot in Barcelona and was released on 12 May 2017.