6 wins & 27 nominations
- 1990 Nominee American Comedy Award
- Funniest Male Performer in a TV Special (Leading or Supporting) Network, Cable or Syndication
For episode "27th Anniversary Show".
- 2008 Nominee People's Choice Award
- Favorite Talk Show Host
- 2007 Nominee People's Choice Award
- Favorite Talk Show Host
- 2006 Winner People's Choice Award
- Favorite Late Night Talk Show Host
- 2005 Nominee People's Choice Award
- Favorite Late Night Talk Show Host
- 2001 Nominee TV Guide Award
- Talk-Variety Star of the Year
- 2014 Winner Mark Twain Prize
- Mark Twain Prize for American Humor
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