- While recording Despicable Me, the directors told her to sing a song about Unicorns and she made one up on the spot.
- Elsie's favourite actor is Steve Carell, with whom she worked on Despicable Me.
- When Elsie grows up she wants to be a scientist, an archaeologist, or a painter.
- Elsie was videotaped while recording her lines for Despicable Me so that the animators could use her speech movements.
- Elsie has a cat named Judy and three dogs named Agnes (also the name of her character in Despicable Me), Ollie, and Allie.
- Elsie started acting at the age of five.
- She has a pet cat named Judy, after Jimmy Neutron's mom.
- Nominated for the 2019 Golden Globe Award in the Best Performance by an Actress in a Motion Picture - Musical or Comedy category for her role as Kayla Day in Eighth Grade (2018), but lost to Olivia Colman for The Favourite (2018).
- Before rising to fame as the voice of Agnes, she appeared in a 2009 episode of the NBC series Medium.
- Elsie has been in over sixteen national commercials.
- For doing such a great job in Despicable Me, Elsie was given a twinkie as a reward.
- Elsie's favourite animal is the giraffe.
- Elsie loved filming her commercial for Hershey's because she got to eat a lot of chocolate.
- She has been playing Pokémon for over 10 years.
- She is of half Scandinavian (Norwegian, Danish), as well as German, English, Swiss-German, Scottish, and distant Irish and Welsh, descent.
- Despises being associated with the Despicable Me (2010) series of films.
- Sister of Nathan Fisher.
- She is best friends with actress Caitlin Carmichael.
- She and George Eads were both in the cast of the 2014 movie Gutshot Straight.
- In 2013, she acted in two episodes of the Fox series Raising Hope. She also starred in the 2018 film Eighth Grade as Kayla.
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