In the ranch of El Soto lives Raymunda (Dolores del Río) and her daughter, Acacia (Columba Domínguez). After she is widowed, Raymunda marries Esteban (Pedro Armendáriz). What Raymunda does not suspect is that a deep passion has arisen between Acacia and Esteban. The misfortune is that the men who approach Acacia have a tragic end, and because of this, they begin to call her "La Malquerida" ("The Unloved").