Eddie and Bess are to be married and their wedding day arrives. A young married couple, Mr. and Mrs. French, are to be their attendants. Their baby is taken sick and they call for the doctor. Before the M.D. arrives, Eddie comes to the house. Fondling the baby, he tries to soothe its wailing until the doctor arrives, when the small red spots on its face and hands are pronounced smallpox. Detective Potts is set to watch the house, assisted by a couple of men. In vain Eddie pleads that it is time for the wedding ceremony. At last he eludes them and runs to the bride's house. The guests crowd about the young couple eagerly. Detective Potts and his men run in and announce that Eddie has smallpox. He leads them a chase, but is finally caught and taken back to the French's home. There another doctor arrives and declares the spots are not smallpox, but prickly heat. Eddie hurries back to his bride.