Sean and Anne bring an allergist, Dr. Austin Chaffee, into their practice. But Austin is an uptight character and has difficulty fitting into the chaos and informality of the Jamieson medical office.
Dr. Sean receives a frantic call and he rushes to the location, thinking it's a children's camp. But to his surprise and chagrin he finds a nudist colony. He tries to maintain his cool while treating the emergency.
Dr. Sean isn't very happy about the rapport developing between daughter Anne and their new colleague Dr. Chaffee. Sean devises various plans to keep the two apart.
When a girl signs up to play for a boy's Little League team all sorts of objections are raised. Dr. Sean tries to make people look at the situation rationally to little avail.
Nurse Puni has taken a second evening job that she is keeping a secret. However it is making Puni so exhausted she is making mistakes at the clinic and Chaffee wants her fired.
After Dr. Chaffee is knocked on the head by a falling coconut Dr. Jamison takes his patients on a temporary basis. But Sean's bedside manner is considered gruff from clients used to Austin's nice ways.
When the rumor spreads the Dr. Sean is a wild party animal his popularity soars. But when he disappoints a few of his dates his reputation suffer and Sean tries set the record straight.
Dr. Sean looks forward to a relaxing day of fishing but he keeps getting detained. Sean finds himself teaching Sunday school and getting Nurse Puni out of jail. Then an emergency delivery of a baby in a parking lot happens.
Dr. Sean enjoys his own little part of the island which he considers paradise. Sean is then outraged when he hears that his landlady has joined with a promoter to build a office complex near him.
Dr. Sean's delivery of quintuplets becomes a media sensation and a stop on the tourism circuit. Sean must figure out a way to put a stop to it to give the parents peace and a chance of normality.
Anne's new boyfriend Jeff is a financial advisor and they are worried about Dr. Sean's future. Jeff convinces the pediatrician to invest in livestock, particularly a $25,000 bull.
The first baby Dr. Sean delivered is now an adult and she shows up to ask a favor. She asks the pediatrician to officiate at a commitment ceremony that has no legal bearing. Sean is undecided how to precede.
Dr. Sean agrees to watch Stewart but is unaware of what he is in for. Sean has difficulty helping with new math homework, finds himself attending an Indian scouts meeting, and finds an appreciation for kiddie cartoons.
Sean's apartment is being painted and daughter Anne generously allows him to move in temporarily. But her carefree lifestyle causes him concern and in spite of himself Sean begins to interfere.
When Sean quits his piano lessons he unwittingly leads an revolt among the children of the community. He must convince the kids the value of getting a musical education.
Dr. Sean is delighted when his old marine buddy Linc arrives to live the island life. He is slightly pertubed when his friend makes a living painting female nudes. He becomes more annoyed when he shows an interest in his daughter Dr. Anne.
Six orphaned children think Dr.Sean would make the perfect father. Sean tries to extricate himself from the situation and yet make the kids life better by finding them a place to live.
Sean is given interest in a catamaran instead of a cash payment. But the boat is unseaworthy and begins to takes all of the pediatrician's time repairing it besides being a money pit.
Dr. Jamison needs to decompress away from all the distractions of the modern world. Sean arranges some time on a remote island but a Captain Tuttle ensures his vacation is anything but relaxing.
A documentary filmmaker wants to make a film about about the Jamison practice. But his presence disrupts the office routine and makes Dr. Sean even more irascible.
Anne's college pal appears and is currently working as a call girl. Dr. Chaffee meets her and a relationship develops. The Jamisons must decide whether to tell their colleague of the woman's profession.