Lu and Dana butt heads over a deceased young woman's fertilized eggs; a dying patient of Lu is in need of a heart transplant; Peter's mother pays a visit.
Dr. Jackson finds himself in hot water after denying a job to a overweight woman; Dana treats a patient who is diagnosed with Gulf War Syndrome; Lana cares for an abandoned newborn baby.
Dana treats a former high school rival who is diagnosed with a brain tumor; an ER nurse plans to sue the hospital after contracting HIV from a patient.
As Lu travels to Puerto Rico where her grandmother needs a bone marrow transplant, she flashes back to her days as a resident and how she met Peter and Lana.
Lu helps out a mother who has been diagnosed with Alzheimer's that is in danger of losing custody of her teenage Down Syndrome son; Dana is concerned about the welfare of a pregnant alcoholic woman.
A patient of Dana's ignores her advice when she decides to have her troubled adoptive teenage daughter undergo rebirthing therapy; Lu treats another patient of Dana's who is sick with tuberculosis.
When Dana's patient gives birth to twins, it's revealed that one baby is black and the other is white; Lu suspects that a woman suffering from chronic back pain has an addiction to prescription drugs; Nick treats a young boy with suspicious bruises.
Dana treats a male acquaintance of hers who is diagnosed with cancer; Lu gets in trouble with the police after defending a diabetic woman who was mistaken as being a drunk driver.
Dana treats a promising young figure skater with osteoporosis who is determined to compete in the Olympics; Lu is not thrilled with the father of Marc's new girlfriend.
Lu helps out a woman with carpal tunnel syndrome whose job won't cover her medical condition; Dana treats a pregnant woman and her teenage son for lead poisoning.
Lu is concerned about the health of the newborn of a wanted female criminal; Dana is concerned when a patient of hers requests breast implants after the first ones rupture.
A nurses' strike affects the hospital which forces Dana to withhold an experimental treatment for a sick baby and delays a medical procedure for an abused patient of Lu's.
Rittenhouse faces a blood shortage; Dana treats a woman who has unknowingly contracted hepatitis from her husband; Lu treats a family with Lyme Disease they contracted from a stray dog that was used in illegal dog fighting.
Lu deals with a life-changing event that makes her the patient for once, and Dr. Stowe has a patient whose dying wish is more difficult to grant than she first thought.
Lu struggles to cope with the aftermath of her rape; Dana has no choice but to turn to Lu's rapist, Dr. Kilner for advice when a pregnant patient of hers is diagnosed with colon cancer.
After Lu discovers that Dr. Kilner will not be prosecuted for raping her, she decides to punish herself instead; Dana's best friend is diagnosed with a fatal lung disease as she is trying to become pregnant.