The team travels to Manhattan to work with the NYPD in tracking and apprehending a serial killer who is intent on dispensing his own style of vigilante justice.
The BAU is requested to assist on a case in Mexico to determine if there is a serial killer in the town of a police captain who attended one of Gideon's seminars.
The BAU team investigates a CIA counter-terrorism unit to identify a traitor who had a fellow agent murdered and who is trying to find and kill the unit's informant, a Saudi woman with two children who are in hiding.
The case of a missing boy placed up for auction online by a child pornographer draws the BAU team to work together with a former profiler who now works for the Innocent Images Unit to find the boy before the auction ends.
The BAU team investigates a series of murders in Florida, suspecting a partnership between two deviant persons with complementary personalities due to the nature of torture videos taken of the victims sent to the victims' parents.
When a bomb is found at what was thought to be a drug lab the BAU is brought in, and while Hotch conducts a state-side investigation Gideon matches wits with a prisoner at Guantánamo Bay.
A young man seeks out Reid for help regarding his fantasies of killing prostitutes, just as a serial killer starts brutalizing prostitutes near the capitol.